Avignon

The surrounding region is full of interesting sites, There are three sites inscribed on the UNESCO World Heritage List

Arles is full of Roman and Romanesque monuments and worthy of a full days exploration. 17mn from Avignon by TER.

Orange just a short train ride to the north is home to one of the finest Roman Theatres in Europe

Le Pont du Gard is about 30km to the West it is probably the finest Roman aquaduct still in existence, and a great place for hiking and canoeing.

Other notable sites nearby are:

Nimes which has a huge Roman ampitheatre and a famous Greek Temple

Châteauneuf-du-Pape is a short train ride north and is home to some of France's most famous vineyards

Aix-en-Provence, town of water - town of art, founded by the Romans.